What is ammonia’s mechanism of action?

Michael Hein
08-08-2017 13:33

Ammonia interacts immediately upon contact with available moisture in the skin, eyes, oral cavity, respiratory tract, and particularly mucous surfaces to form the very caustic ammonium hydroxide. Ammonium hydroxide causes the necrosis of tissues through disruption of cell membrane lipids (saponification) leading to cellular destruction. As cell proteins break down, water is extracted, resulting in an inflammatory response that causes further damage.

Text source: www.health.ny.gov

 

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